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STAT3 (phospho Y705), Rabbit anti-Human, Mouse, Polyclonal Antibody, Abnova™

Catalog No. 89126398 Shop All Abnova Corporation Products
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100 μL
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89-126-398 100 μL
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Catalog No. 89-126-398 Supplier Abnova Corporation Supplier No. PAB24732
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Description

Rabbit polyclonal antibody raised against synthetic phosphopeptide of STAT3.

The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs, EGF, IL5, IL6, HGF, LIF and BMP2. This protein mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis. The small GTPase Rac1 has been shown to bind and regulate the activity of this protein. PIAS3 protein is a specific inhibitor of this protein. Three alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq

Specifications

Antigen STAT3
Applications Western Blot
Classification Polyclonal
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic phosphopeptide of STAT3.
Dilution Western Blot (1:500-1:1000) The optimal working dilution should be determined by the end user.
Formulation In PBS, pH 7.2 (0.09% sodium azide)
Gene STAT3
Gene Alias APRF/FLJ20882/HIES/MGC16063
Gene Symbols STAT3
Host Species Rabbit
Immunogen Synthetic phosphopeptide corresponding to residues surrounding Y705 of STAT3.
Purification Method Antigen affinity purification
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 6774
Test Specificity STAT3 (phospho Y705) polyclonal antibody detects endogenous levels of STAT3 protein.
Target Species Human, Mouse
Content And Storage Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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