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STAT5A (phospho S726), Rabbit anti-Human, Polyclonal Antibody, Abnova™

Catalog No. 89114306 Shop All Abnova Corporation Products
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400 μL
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89-114-306 400 μL
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Catalog No. 89-114-306 Supplier Abnova Corporation Supplier No. PAB0620
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Description

Rabbit polyclonal antibody raised against synthetic phosphopeptide of STAT5A.

The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated by, and mediates the responses of many cell ligands, such as IL2, IL3, IL7 GM-CSF, erythropoietin, thrombopoietin, and different growth hormones. Activation of this protein in myeloma and lymphoma associated with a TEL/JAK2 gene fusion is independent of cell stimulus and has been shown to be essential for the tumorigenesis. The mouse counterpart of this gene is found to induce the expression of BCL2L1/BCL-X(L), which suggests the antiapoptotic function of this gene in cells. [provided by RefSeq

Specifications

Antigen STAT5A
Applications Dot Blot, ELISA, Immunohistochemistry, Western Blot
Classification Polyclonal
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic phosphopeptide of STAT5A.
Dilution Western Blot (1:1000) Immunohistochemistry (1:50-100) Dot Blot (1:500) The optimal working dilution should be determined by the end user.
Formulation In PBS (0.09% sodium azide)
Gene STAT5A
Gene Alias MGF/STAT5
Gene Symbols STAT5A
Host Species Rabbit
Immunogen Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding S726 of human STAT5A.
Purification Method Protein G purification
Quantity 400 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 6776
Target Species Human
Content And Storage Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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