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STAT5A Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™

Catalog No. 89119944 Shop All Abnova Corporation Products
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100 μg
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Catalog No. Quantity
89-119-944 100 μg
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Catalog No. 89-119-944 Supplier Abnova Corporation Supplier No. PAB18379
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Description

Rabbit polyclonal antibody raised against synthetic peptide of STAT5A.

The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated by, and mediates the responses of many cell ligands, such as IL2, IL3, IL7 GM-CSF, erythropoietin, thrombopoietin, and different growth hormones. Activation of this protein in myeloma and lymphoma associated with a TEL/JAK2 gene fusion is independent of cell stimulus and has been shown to be essential for the tumorigenesis. The mouse counterpart of this gene is found to induce the expression of BCL2L1/BCL-X(L), which suggests the antiapoptotic function of this gene in cells. [provided by RefSeq

Specifications

Antigen STAT5A
Applications ELISA, Immunohistochemistry (PFA fixed)
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic peptide of STAT5A.
Dilution Immunohistochemistry (1:50-1:100) ELISA (1:5000) The optimal working dilution should be determined by the end user.
Formulation In PBS, 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
Gene STAT5A
Gene Alias MGF/STAT5
Gene Symbols STAT5A
Host Species Rabbit
Immunogen A synthetic peptide corresponding to human STAT5A.
Purification Method Affinity purification
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 6776
Test Specificity This antibody is specific to STAT5A.
Target Species Human, Mouse, Rat
Content And Storage Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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