STAT6 Rabbit anti-Human, Polyclonal Antibody, Abnova™

Catalog No.	Quantity
89-128-275	100 μg

Catalog No. 89-128-275 Supplier Abnova Corporation Supplier No. PAB26638

Description

Rabbit polyclonal antibody raised against synthetic peptide of STAT6.

The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. [provided by RefSeq

Sequence: P-A-Tp-I-K

Specifications

• Antigen: STAT6
• Applications: Immunohistochemistry (PFA fixed), Western Blot
• Classification: Polyclonal
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Description: Rabbit polyclonal antibody raised against synthetic peptide of STAT6.
• Dilution: Western Blot (1:500-1:1000) Immunohistochemistry (1:50-1:100) The optimal working dilution should be determined by the end user.
• Formulation: In PBS (without Mg²⁺ and Ca²⁺), 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
• Gene: STAT6
• Gene Alias: D12S1644/IL-4-STAT/STAT6B/STAT6C
• Gene Symbols: STAT6
• Host Species: Rabbit
• Immunogen: A synthetic peptide corresponding to residues surrounding T645 of human STAT6.
• Purification Method: Affinity chromatography
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 6778
• Target Species: Human
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid

For Research Use Only