STIM1 Rabbit anti-Bovine, Dog, Human, Mouse, Pig, Rat, Polyclonal Antibody, Abnova™

Catalog No.	Quantity
89-115-527	100 μL

Catalog No. 89-115-527 Supplier Abnova Corporation Supplier No. PAB12017

Description

Rabbit polyclonal antibody raised against synthetic peptide of STIM1.

This gene encodes a type 1 transmembrane protein that mediates Ca2+ influx after depletion of intracellular Ca2+ stores by gating of store-operated Ca2+ influx channels (SOCs). It is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocrotical carcinoma, and lung, ovarian, and breast cancer. This gene may play a role in malignancies and disease that involve this region, as well as early hematopoiesis, by mediating attachment to stromal cells. This gene is oriented in a head-to-tail configuration with the ribonucleotide reductase 1 gene (RRM1), with the 3' end of this gene situated 1.6kb from the 5' end of the RRM1 gene

Specifications

• Antigen: STIM1
• Applications: Immunocytochemistry, Immunofluorescence, Western Blot
• Classification: Polyclonal
• Conjugate: Unconjugated
• Description: Rabbit polyclonal antibody raised against synthetic peptide of STIM1.
• Dilution: Immunocytochemistry (1:50-1:200) Immunofluorescence (1:50-1:200) The optimal working dilution should be determined by the end user.
• Formulation: In PBS (30% glycerol, 0.09% sodium azide)
• Gene: STIM1
• Gene Alias: D11S4896E/GOK
• Gene Symbols: STIM1
• Host Species: Rabbit
• Immunogen: A synthetic peptide corresponding to amino acids 600-685 of human STIM1.
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 6786
• Target Species: Bovine, Canine, Human, Mouse, Pig, Rat
• Content And Storage: Store at 4°C for short term. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid

For Research Use Only