STRADA (LYK5), Rabbit, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic peptide of LYK5.

Supplier:  Abnova Corporation PAB0376

Catalog No. 89-114-188

Description

The protein encoded by this gene contains a STE20-like kinase domain, but lacks several residues that are critical for catalytic activity, so it is termed a 'pseudokinase'. The protein forms a heterotrimeric complex with serine/threonine kinase 11 (STK11, also known as LKB1) and the scaffolding protein calcium binding protein 39 (CAB39, also known as MO25). The protein activates STK11 leading to the phosphorylation of both proteins and excluding STK11 from the nucleus. The protein is necessary for STK11-induced G1 cell cycle arrest. A mutation in this gene has been shown to result in polyhydramnios, megalencephaly, and symptomatic epilepsy (PMSE) syndrome. Multiple transcript variants encoding different isoforms have been found for this gene. Additional transcript variants have been described but their full-length nature is not known. [provided by RefSeq]

Specifications

• Antigen: STRADA (LYK5)
• Classification: Polyclonal
• Description: Rabbit polyclonal antibody raised against synthetic peptide of LYK5.
• Formulation: In PBS (0.05% BSA, 0.05% sodium azide)
• Gene Alias: FLJ90524/LYK5/NY-BR-96/PMSE/STRAD/Stlk
• Host Species: Rabbit
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Form: Liquid

• Applications: Western Blot
• Conjugate: Unconjugated
• Dilution: The optimal working dilution should be determined by the end user.
• Gene: STRADA
• Gene Symbols: STRADA
• Immunogen: A synthetic peptide corresponding to amino acids 300-350 of human LYK5.
• Regulatory Status: RUO
• Gene ID (Entrez): 92335
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.

For Research Use Only