TBK1, Rabbit, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic peptide of TBK1.

Supplier:  Abnova Corporation PAB12859

Catalog No. 89-116-137

Description

The NF-kappa-B (NFKB) complex of proteins is inhibited by I-kappa-B (IKB) proteins, which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the IKB proteins by IKB kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation and nuclear translocation of the NFKB complex. The protein encoded by this gene is similar to IKB kinases and can mediate NFKB activation in response to certain growth factors. For example, the protein can form a complex with the IKB protein TANK and TRAF2 and release the NFKB inhibition caused by TANK. [provided by RefSeq

Specifications

• Antigen: TBK1
• Classification: Polyclonal
• Description: Rabbit polyclonal antibody raised against synthetic peptide of TBK1.
• Formulation: In PBS (0.02% sodium azide)
• Gene Alias: FLJ11330/NAK/T2K
• Host Species: Rabbit
• Quantity: 100 μg
• Primary or Secondary: Primary
• Test Specificity: A 84 KDa band should be detected. It is human, mouse and rat reactive and has no cross response to IKKa, IKKb, IKKy, or IKKe.
• Content And Storage: Store at 4°C for three months. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.

• Applications: Immunocytochemistry, Western Blot
• Conjugate: Unconjugated
• Dilution: Western Blot (0.5-1 ug/mL) The optimal working dilution should be determined by the end user.
• Gene: TBK1
• Gene Symbols: TBK1
• Immunogen: A synthetic peptide corresponding to C-terminus 17 amino acids of human TBK1.
• Regulatory Status: RUO
• Gene ID (Entrez): 29110
• Target Species: Human, Mouse
• Form: Liquid

For Research Use Only