MilliporeSigma™ Rabbit anti-TDP-43, Polyclonal,

Rabbit Polyclonal Antibody

Supplier:  MilliporeSigma™ ABN895

Catalog No. ABN895MI

Description

Specifically detects TDP-43 in Human samples, and it is validated for Immunocytochemistry, Western Blotting

TAR DNA-binding protein 43 (TDP-43) belongs to the hnRNP protein family and plays an important role in transcription, pre-mRNA splicing, mRNA stability and mRNA transport. It is involved in splicing of the apolipoprotein A-II and cystic fibrosis transmembrane gene. This protein is highly expressed in the pancreas, placenta, lung, genital tract and spleen. Mutations in TDP-43 have been associated with amyotrophic lateral sclerosis, frontotemporal dementia, Parkinson's disease and Alzheimer's disease.

Specifications

• Antigen: TDP-43
• Classification: Polyclonal
• Gene Accession No.: Q13148
• Host Species: Rabbit
• Purification Method: Affinity Purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Content And Storage: Stable for one year at 2°C to 8°C from date of receipt.

• Applications: Immunocytochemistry, Western Blot
• Formulation: Purified rabbit polyclonal in buffer containing PBS (pH 7.2) with 0.02% sodium azide.
• Gene Symbols: TARDBP; TDP43
• Immunogen: TDP43 antibody was raised against a 15 amino acid synthetic peptide from near the carboxy terminus of human TDP43.
• Quantity: 100 μg
• Research Discipline: Neuroscience
• Target Species: Human

For Research Use Only