TGFBR2 Rabbit anti-Human, Mouse, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic peptide of TGFBR2.

Supplier:  Abnova Corporation PAB27131

Catalog No. 89-128-784

Description

This gene encodes a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. The encoded protein is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with another receptor protein, and binds TGF-beta. This receptor/ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of a subset of genes related to cell proliferation. Mutations in this gene have been associated with Marfan Syndrome, Loeys-Deitz Aortic Aneurysm Syndrome, and the development of various types of tumors. Alternatively spliced transcript variants encoding different isoforms have been characterized. [provided by RefSeq

Specifications

• Antigen: TGFBR2
• Classification: Polyclonal
• Description: Rabbit polyclonal antibody raised against synthetic peptide of TGFBR2.
• Formulation: In PBS, pH 7.2 (0.05% sodium azide)
• Gene Alias: AAT3/FAA3/LDS1B/LDS2B/MFS2/RIIC/TAAD2/TGFR-2/TGFbeta-RII
• Host Species: Rabbit
• Purification Method: Antigen affinity purification
• Regulatory Status: RUO
• Gene ID (Entrez): 7048
• Target Species: Human, Mouse
• Form: Liquid

• Applications: Immunohistochemistry (PFA fixed), Western Blot
• Conjugate: Unconjugated
• Dilution: Western Blot (1:500-1:1000) Immunohistochemistry (1:50-1:200) The optimal working dilution should be determined by the end user.
• Gene: TGFBR2
• Gene Symbols: TGFBR2
• Immunogen: A synthetic peptide corresponding to to amino acids 220-300 of human TGFBR2.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Test Specificity: TGFBR2 polyclonal antibody detects endogenous levels of TGFBR2 protein.
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.

For Research Use Only