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TGFBR2 (phospho S225/S250), Rabbit anti-Human, Polyclonal Antibody, Abnova™

Catalog No. 89130720 Shop All Abnova Corporation Products
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89-130-720 100 μL
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Catalog No. 89-130-720 Supplier Abnova Corporation Supplier No. PAB29283
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Description

Rabbit polyclonal antibody raised against synthetic phosphopeptide of human TGFBR2.

This gene encodes a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. The encoded protein is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with another receptor protein, and binds TGF-beta. This receptor/ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of a subset of genes related to cell proliferation. Mutations in this gene have been associated with Marfan Syndrome, Loeys-Deitz Aortic Aneurysm Syndrome, and the development of various types of tumors. Alternatively spliced transcript variants encoding different isoforms have been characterized. [provided by RefSeq

Specifications

Antigen TGFBR2
Applications Immunohistochemistry (PFA fixed)
Classification Polyclonal
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic phosphopeptide of human TGFBR2.
Dilution Immunohistochemistry (1:50∼1:100) The optimal working dilution should be determined by the end user.
Formulation In PBS (without Mg2+ and Ca2+), 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
Gene TGFBR2
Gene Alias AAT3/FAA3/LDS1B/LDS2B/MFS2/RIIC/TAAD2/TGFR-2/TGFbeta-RII
Gene Symbols TGFBR2
Host Species Rabbit
Immunogen Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding S225/S250 of human TGFBR2.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 7048
Test Specificity TGFBR2 (phospho S225/S250) polyclonal antibody detects endogenous levels of human TGFBR2 only when phosphorylated at serine 225/250.
Target Species Human
Content And Storage Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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