TGFBR2 (phospho S225/S250), Rabbit anti-Human, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic phosphopeptide of human TGFBR2.

Supplier:  Abnova Corporation PAB29283

Catalog No. 89-130-720

Description

This gene encodes a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. The encoded protein is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with another receptor protein, and binds TGF-beta. This receptor/ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of a subset of genes related to cell proliferation. Mutations in this gene have been associated with Marfan Syndrome, Loeys-Deitz Aortic Aneurysm Syndrome, and the development of various types of tumors. Alternatively spliced transcript variants encoding different isoforms have been characterized. [provided by RefSeq

Specifications

• Antigen: TGFBR2
• Classification: Polyclonal
• Description: Rabbit polyclonal antibody raised against synthetic phosphopeptide of human TGFBR2.
• Formulation: In PBS (without Mg²⁺ and Ca²⁺), 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
• Gene Alias: AAT3/FAA3/LDS1B/LDS2B/MFS2/RIIC/TAAD2/TGFR-2/TGFbeta-RII
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 7048
• Target Species: Human
• Form: Liquid

• Applications: Immunohistochemistry (PFA fixed)
• Conjugate: Unconjugated
• Dilution: Immunohistochemistry (1:50∼1:100) The optimal working dilution should be determined by the end user.
• Gene: TGFBR2
• Gene Symbols: TGFBR2
• Immunogen: Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding S225/S250 of human TGFBR2.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Test Specificity: TGFBR2 (phospho S225/S250) polyclonal antibody detects endogenous levels of human TGFBR2 only when phosphorylated at serine 225/250.
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.

For Research Use Only