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THRB Rabbit anti-Human, Polyclonal Antibody, Abnova™

Catalog No. 89115407 Shop All Abnova Corporation Products
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89-115-407 100 μL
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Catalog No. 89-115-407 Supplier Abnova Corporation Supplier No. PAB11824

Description

Rabbit polyclonal antibody raised against synthetic peptide of THRB.

The protein encoded by this gene is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for thyroid hormone, and has been shown to mediate the biological activities of thyroid hormone. Knockout studies in mice suggest that the different receptors, while having certain extent of redundancy, may mediate different functions of thyroid hormone. Mutations in this gene are known to be a cause of generalized thyroid hormone resistance (GTHR), a syndrome characterized by goiter and high levels of circulating thyroid hormone (T3-T4), with normal or slightly elevated thyroid stimulating hormone (TSH). Several alternatively spliced transcript variants encoding the same protein have been observed for this gene. [provided by RefSeq

Specifications

Antigen THRB
Applications Immunohistochemistry (PFA fixed)
Classification Polyclonal
Concentration Lot specific
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic peptide of THRB.
Dilution Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (Formalin/PFA-fixed paraffin-embedded sections) (1:100) The optimal working dilution should be determined by the end user.
Formulation In 10mM PBS, pH 7.4 (1% BSA, 0.09% sodium azide)
Gene THRB
Gene Alias ERBA-BETA/ERBA2/GRTH/MGC126109/MGC126110/NR1A2/PRTH/THR1/THRB1/THRB2
Gene Symbols THRB
Host Species Rabbit
Immunogen A synthetic peptide corresponding to amino acids 31-50 of human THRB.
Purification Method Immunoaffinity purification
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 7068
Target Species Human
Content And Storage Store at 4°C.
Form Liquid
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For Research Use Only

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