THRB Rabbit anti-Human, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic peptide of THRB.

Supplier:  Abnova Corporation PAB11824

Catalog No. 89-115-407

Description

The protein encoded by this gene is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for thyroid hormone, and has been shown to mediate the biological activities of thyroid hormone. Knockout studies in mice suggest that the different receptors, while having certain extent of redundancy, may mediate different functions of thyroid hormone. Mutations in this gene are known to be a cause of generalized thyroid hormone resistance (GTHR), a syndrome characterized by goiter and high levels of circulating thyroid hormone (T3-T4), with normal or slightly elevated thyroid stimulating hormone (TSH). Several alternatively spliced transcript variants encoding the same protein have been observed for this gene. [provided by RefSeq

Specifications

• Antigen: THRB
• Classification: Polyclonal
• Conjugate: Unconjugated
• Dilution: Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (Formalin/PFA-fixed paraffin-embedded sections) (1:100) The optimal working dilution should be determined by the end user.
• Gene: THRB
• Gene Symbols: THRB
• Immunogen: A synthetic peptide corresponding to amino acids 31-50 of human THRB.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Form: Liquid

• Applications: Immunohistochemistry (PFA fixed)
• Concentration: Lot specific
• Description: Rabbit polyclonal antibody raised against synthetic peptide of THRB.
• Formulation: In 10mM PBS, pH 7.4 (1% BSA, 0.09% sodium azide)
• Gene Alias: ERBA-BETA/ERBA2/GRTH/MGC126109/MGC126110/NR1A2/PRTH/THR1/THRB1/THRB2
• Host Species: Rabbit
• Purification Method: Immunoaffinity purification
• Regulatory Status: RUO
• Gene ID (Entrez): 7068
• Content And Storage: Store at 4°C.

For Research Use Only