TIMP1 Rabbit anti-Human, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic peptide of TIMP1.

Supplier:  Abnova Corporation PAB19116

Catalog No. 89-120-648

Description

This gene belongs to the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function. Transcription of this gene is highly inducible in response to many cytokines and hormones. In addition, the expression from some but not all inactive X chromosomes suggests that this gene inactivation is polymorphic in human females. This gene is located within intron 6 of the synapsin I gene and is transcribed in the opposite direction. [provided by RefSeq

Specifications

• Antigen: TIMP1
• Classification: Polyclonal
• Description: Rabbit polyclonal antibody raised against synthetic peptide of TIMP1.
• Formulation: Lyophilized from 0.9mg NaCl, 0.2mg Na₂HPO₄ (5mg BSA, 0.05mg sodium azide, 0.05mg Thimerosal)
• Gene Alias: CLGI/EPA/EPO/FLJ90373/HCI/TIMP
• Host Species: Rabbit
• Purification Method: Immunoaffinity purification
• Regulatory Status: RUO
• Gene ID (Entrez): 7076
• Content And Storage: Store at -20°C on dry atmosphere. After reconstitution with 200μL of deionized water to a concentration of 500μg/mL store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
• Isotype: IgG

• Applications: Immunohistochemistry (PFA fixed), Western Blot
• Conjugate: Unconjugated
• Dilution: Western Blot (1 ug/mL) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1 ug/mL) The optimal working dilution should be determined by the end user.
• Gene: TIMP1
• Gene Symbols: TIMP1
• Immunogen: A synthetic peptide corresponding to C-terminus of human TIMP1.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Form: Lyophilized

For Research Use Only