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Description
This gene encodes a highly glycosylated transmembrane protein with a high content of threonine and serine residues in its extracellular domain, similar to a broadly defined category of proteins termed mucins. Exposure of some cell types to anti-PORIMIN (pro-oncosis receptor inducing membrane injury) antibody, crosslinks this protein on the cell surface and induces a type of cell death termed oncosis. Oncosis is distinct from apoptosis and is characterized by a loss of cell membrane integrity without DNA fragmentation. This gene product is proposed to function as a cell surface receptor that mediates cell death. [provided by RefSeq
Specifications
Specifications
| Antigen | TMEM123 |
| Applications | Western Blot |
| Classification | Polyclonal |
| Conjugate | Unconjugated |
| Description | Rabbit polyclonal antibody raised against synthetic peptide of TMEM123. |
| Dilution | The optimal working dilution should be determined by the end user. |
| Formulation | In PBS (0.2% gelatin, 0.05% sodium azide) |
| Gene | TMEM123 |
| Gene Alias | KCT3/PORIMIN/PORMIN |
| Gene Symbols | TMEM123 |
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