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Description
This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biologic processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene functions as a tumor necrosis factor-alpha converting enzyme; binds mitotic arrest deficient 2 protein; and also plays a prominent role in the activation of the Notch signaling pathway. [provided by RefSeq
Specifications
Specifications
| Antigen | TNF |
| Applications | ELISA, Immunoprecipitation |
| Classification | Polyclonal |
| Conjugate | Unconjugated |
| Description | Rabbit polyclonal antibody raised against recombinant TNF. |
| Dilution | The optimal working dilution should be determined by the end user. |
| Formulation | In PBS, pH 7.5 (50% glycerol, 0.01% thimerosal) |
| Gene | ADAM17 |
| Gene Alias | CD156b/MGC71942/TACE/cSVP |
| Gene Symbols | ADAM17 |
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