TNFRSF10C Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic peptide of TNFRSF10C.

Supplier:  Abnova Corporation PAB13081

Catalog No. 89-116-334

Description

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains an extracellular TRAIL-binding domain and a transmembrane domain, but no cytoplasmic death domain. This receptor is not capable of inducing apoptosis, and is thought to function as an antagonistic receptor that protects cells from TRAIL-induced apoptosis. This gene was found to be a p53-regulated DNA damage-inducible gene. The expression of this gene was detected in many normal tissues but not in most cancer cell lines, which may explain the specific sensitivity of cancer cells to the apoptosis-inducing activity of TRAIL. [provided by RefSeq

Specifications

• Antigen: TNFRSF10C
• Classification: Polyclonal
• Description: Rabbit polyclonal antibody raised against synthetic peptide of TNFRSF10C.
• Formulation: In PBS (0.02% sodium azide)
• Gene Alias: CD263/DCR1/LIT/MGC149501/MGC149502/TRAILR3/TRID
• Host Species: Rabbit
• Quantity: 100 μg
• Primary or Secondary: Primary
• Test Specificity: An approximate 65 KDa band can be detected. It is human, mouse, and rat reactive.
• Content And Storage: Store at 4°C for three months. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.

• Applications: Immunocytochemistry, Western Blot
• Conjugate: Unconjugated
• Dilution: Western Blot (1:500-1:1000) The optimal working dilution should be determined by the end user.
• Gene: TNFRSF10C
• Gene Symbols: TNFRSF10C
• Immunogen: A synthetic peptide corresponding to amino acids in an extracellular domain of human TNFRSF10C.
• Regulatory Status: RUO
• Gene ID (Entrez): 8794
• Target Species: Human, Mouse, Rat
• Form: Liquid

For Research Use Only