TNFRSF13C Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic peptide of TNFRSF13C.

Supplier:  Abnova Corporation PAB12894

Catalog No. 89-116-168

Description

B cell-activating factor (BAFF) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. Overexpression of Baff in mice results in mature B-cell hyperplasia and symptoms of systemic lupus erythematosus (SLE). Also, some SLE patients have increased levels of BAFF in serum. Therefore, it has been proposed that abnormally high levels of BAFF may contribute to the pathogenesis of autoimmune diseases by enhancing the survival of autoreactive B cells. The protein encoded by this gene is a receptor for BAFF and is a type III transmembrane protein containing a single extracellular cysteine-rich domain. It is thought that this receptor is the principal receptor required for BAFF-mediated mature B-cell survival. [provided by RefSeq

Specifications

• Antigen: TNFRSF13C
• Classification: Polyclonal
• Description: Rabbit polyclonal antibody raised against synthetic peptide of TNFRSF13C.
• Formulation: In PBS (0.02% sodium azide)
• Gene Alias: BAFF-R/BAFFR/CD268/MGC138235
• Host Species: Rabbit
• Quantity: 100 μg
• Primary or Secondary: Primary
• Test Specificity: The peptide sequence is identical between human and mouse origin.
• Content And Storage: Store at 4°C for three months. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.

• Applications: Immunohistochemistry (PFA fixed), Western Blot
• Conjugate: Unconjugated
• Dilution: Western Blot (2-5 ug/mL) The optimal working dilution should be determined by the end user.
• Gene: TNFRSF13C
• Gene Symbols: TNFRSF13C
• Immunogen: A synthetic peptide corresponding to amino acids near C-terminus of human TNFRSF13C.
• Regulatory Status: RUO
• Gene ID (Entrez): 115650
• Target Species: Human, Mouse, Rat
• Form: Liquid

For Research Use Only