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TNFRSF13C Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™

Catalog No. 89116168 Shop All Abnova Corporation Products
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89-116-168 100 μg
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Catalog No. 89-116-168 Supplier Abnova Corporation Supplier No. PAB12894
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Rabbit polyclonal antibody raised against synthetic peptide of TNFRSF13C.

B cell-activating factor (BAFF) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. Overexpression of Baff in mice results in mature B-cell hyperplasia and symptoms of systemic lupus erythematosus (SLE). Also, some SLE patients have increased levels of BAFF in serum. Therefore, it has been proposed that abnormally high levels of BAFF may contribute to the pathogenesis of autoimmune diseases by enhancing the survival of autoreactive B cells. The protein encoded by this gene is a receptor for BAFF and is a type III transmembrane protein containing a single extracellular cysteine-rich domain. It is thought that this receptor is the principal receptor required for BAFF-mediated mature B-cell survival. [provided by RefSeq

Specifications

Antigen TNFRSF13C
Applications Immunohistochemistry (PFA fixed), Western Blot
Classification Polyclonal
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic peptide of TNFRSF13C.
Dilution Western Blot (2-5 ug/mL) The optimal working dilution should be determined by the end user.
Formulation In PBS (0.02% sodium azide)
Gene TNFRSF13C
Gene Alias BAFF-R/BAFFR/CD268/MGC138235
Gene Symbols TNFRSF13C
Host Species Rabbit
Immunogen A synthetic peptide corresponding to amino acids near C-terminus of human TNFRSF13C.
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 115650
Test Specificity The peptide sequence is identical between human and mouse origin.
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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