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TNFRSF1B Rabbit anti-Human, Polyclonal Antibody, Abnova™

Catalog No. 89115723 Shop All Abnova Corporation Products
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100 μg
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89-115-723 100 μg
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Catalog No. 89-115-723 Supplier Abnova Corporation Supplier No. PAB12329
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Description

Rabbit polyclonal antibody raised against synthetic peptide of TNFRSF1B.

The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein and TNF-receptor 1 form a heterocomplex that mediates the recruitment of two anti-apoptotic proteins, c-IAP1 and c-IAP2, which possess E3 ubiquitin ligase activity. The function of IAPs in TNF-receptor signalling is unknown, however, c-IAP1 is thought to potentiate TNF-induced apoptosis by the ubiquitination and degradation of TNF-receptor-associated factor 2, which mediates anti-apoptotic signals. Knockout studies in mice also suggest a role of this protein in protecting neurons from apoptosis by stimulating antioxidative pathways. [provided by RefSeq

Specifications

Antigen TNFRSF1B
Applications Immunohistochemistry (PFA fixed), Western Blot
Classification Polyclonal
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic peptide of TNFRSF1B.
Dilution Western Blot (1 ug/mL) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1 ug/mL) The optimal working dilution should be determined by the end user.
Formulation Lyophilized from 0.9mg NaCl, 0.2mg Na2HPO4 (5mg BSA, 0.05mg sodium azide, 0.05mg Thimerosal)
Gene TNFRSF1B
Gene Alias CD120b/TBPII/TNF-R-II/TNF-R75/TNFBR/TNFR1B/TNFR2/TNFR80/p75/p75TNFR
Gene Symbols TNFRSF1B
Host Species Rabbit
Immunogen A synthetic peptide corresponding to amino acids at N-terminus of human TNFRSF1B.
Purification Method Immunoaffinity purification
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 7133
Target Species Human
Content And Storage Store at -20°C on dry atmosphere. After reconstitution with 200μL of deionized water to a concentration of 500μg/mL store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Form Lyophilized
Isotype IgG
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