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TNFSF10 Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™

Catalog No. 89114469 Shop All Abnova Corporation Products
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200 μg
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89-114-469 200 μg
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Catalog No. 89-114-469 Supplier Abnova Corporation Supplier No. PAB0842
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Description

Rabbit polyclonal antibody raised against a synthetic peptide of TNFSF10.

The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein preferentially induces apoptosis in transformed and tumor cells, but does not appear to kill normal cells although it is expressed at a significant level in most normal tissues. This protein binds to several members of TNF receptor superfamily including TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4, and possibly also to TNFRSF11B/OPG. The activity of this protein may be modulated by binding to the decoy receptors TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4, and TNFRSF11B/OPG that cannot induce apoptosis. The binding of this protein to its receptors has been shown to trigger the activation of MAPK8/JNK, caspase 8, and caspase 3. [provided by RefSeq

Specifications

Antigen TNFSF10
Applications Western Blot
Classification Polyclonal
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against a synthetic peptide of TNFSF10.
Dilution Western Blot (1:200) The optimal working dilution should be determined by the end user.
Formulation In PBS (0.2% gelatin, 0.09% sodium azide)
Gene TNFSF10
Gene Alias APO2L/Apo-2L/CD253/TL2/TRAIL
Gene Symbols TNFSF10
Host Species Rabbit
Immunogen A synthetic peptide (conjugated with KLH) corresponding to C-terminus human TNFSF10.
Quantity 200 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 8743
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C. Do not freeze.
Form Liquid
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For Research Use Only

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