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Description
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptor TNFRSF4/OX4. It is found to be involved in T cell antigen-presenting cell (APC) interactions. In surface Ig- and CD40-stimulated B cells, this cytokine along with CD70 has been shown to provide CD28-independent costimulatory signals to T cells. This protein and its receptor are reported to directly mediate adhesion of activated T cells to vascular endothelial cells. [provided by RefSeq
Specifications
Specifications
| Antigen | TNFSF4 |
| Applications | ELISA, Immunofluorescence, Immunohistochemistry, Western Blot |
| Classification | Polyclonal |
| Concentration | 1 mg/mL |
| Conjugate | Unconjugated |
| Description | Rabbit polyclonal antibody raised against synthetic peptide of TNFSF4. |
| Dilution | Western Blot (0.5-1 ug/mL) Immunohistochemistry (5 ug/mL) Immunofluorescence (20 ug/mL) The optimal working dilution should be determined by the end user. |
| Formulation | In PBS (0.02% sodium azide) |
| Gene | TNFSF4 |
| Gene Alias | CD134L/CD252/GP34/OX-40L/OX4OL/TXGP1 |
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