TNK2 (phospho Y284), Rabbit anti-Human, Polyclonal Antibody, Abnova™
Rabbit polyclonal antibody raised against synthetic phosphopeptide of human TNK2.
Supplier: Abnova Corporation PAB29267
This gene encodes a tyrosine kinase that binds Cdc42Hs in its GTP-bound form and inhibits both the intrinsic and GTPase-activating protein (GAP)-stimulated GTPase activity of Cdc42Hs. This binding is mediated by a unique sequence of 47 amino acids C-terminal to an SH3 domain. The protein may be involved in a regulatory mechanism that sustains the GTP-bound active form of Cdc42Hs and which is directly linked to a tyrosine phosphorylation signal transduction pathway. Several alternatively spliced transcript variants have been identified from this gene, but the full-length nature of only two transcript variants has been determined. [provided by RefSeq
|Rabbit polyclonal antibody raised against synthetic phosphopeptide of human TNK2.
|In PBS (without Mg2+ and Ca2+), 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
|Immunofluorescence, Immunohistochemistry (PFA fixed), Western Blot
|Immunofluorescence (1:100∼1:200) Immunohistochemistry (1:50∼1:100) Western Blot (1:500∼1:1000) The optimal working dilution should be determined by the end user.
|Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding Y284 of human TNK2.
|TNK2 (phospho Y284) polyclonal antibody detects endogenous levels of human TNK2 only when phosphorylated at tyrosine 284.
|Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
For Research Use Only