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TNK2 (phospho Y284), Rabbit anti-Human, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic phosphopeptide of human TNK2.

Supplier:  Abnova Corporation PAB29267

Catalog No. 89-130-704


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Description

Description

This gene encodes a tyrosine kinase that binds Cdc42Hs in its GTP-bound form and inhibits both the intrinsic and GTPase-activating protein (GAP)-stimulated GTPase activity of Cdc42Hs. This binding is mediated by a unique sequence of 47 amino acids C-terminal to an SH3 domain. The protein may be involved in a regulatory mechanism that sustains the GTP-bound active form of Cdc42Hs and which is directly linked to a tyrosine phosphorylation signal transduction pathway. Several alternatively spliced transcript variants have been identified from this gene, but the full-length nature of only two transcript variants has been determined. [provided by RefSeq

Specifications

Specifications

TNK2
Polyclonal
Rabbit polyclonal antibody raised against synthetic phosphopeptide of human TNK2.
In PBS (without Mg2+ and Ca2+), 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
ACK/ACK1/FLJ44758/FLJ45547/p21cdc42Hs
Rabbit
Affinity Chromatography
RUO
10188
Human
Liquid
Immunofluorescence, Immunohistochemistry (PFA fixed), Western Blot
Unconjugated
Immunofluorescence (1:100∼1:200) Immunohistochemistry (1:50∼1:100) Western Blot (1:500∼1:1000) The optimal working dilution should be determined by the end user.
TNK2
TNK2
Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding Y284 of human TNK2.
100 μL
Primary
TNK2 (phospho Y284) polyclonal antibody detects endogenous levels of human TNK2 only when phosphorylated at tyrosine 284.
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
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