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Description
Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM). [provided by RefSeq
Specifications
Specifications
| Antigen | TNNI3 |
| Applications | ELISA, Western Blot |
| Classification | Polyclonal |
| Conjugate | Unconjugated |
| Description | Rabbit polyclonal antibody raised against full length recombinant TNNI3. |
| Dilution | Western blot (1:500) The optimal working dilution should be determined by the end user. |
| Formulation | In serum |
| Gene | TNNI3 |
| Gene Alias | CMD2A/CMH7/MGC116817/RCM1/TNNC1/cTnI |
| Gene Symbols | TNNI3 |
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