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TOB1, Rabbit, Polyclonal Antibody, Abnova™

Catalog No. 89130690 Shop All Abnova Corporation Products
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89-130-690 100 μL
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Catalog No. 89-130-690 Supplier Abnova Corporation Supplier No. PAB29253
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Rabbit polyclonal antibody raised against synthetic phosphopeptide of human TOB1.

This gene encodes a member of the tob/btg1 family of anti-proliferative proteins that have the potential to regulate cell growth. When exogenously expressed, this protein supresses cell growth in tissue culture. The protein undergoes phophorylation by a serine/threonine kinase, 90kDa ribosomal S6 kinase. Interactions of this protein with the v-erb-b2 erythroblastic leukemia viral oncogene homolog 2 gene product p185 interferes with growth suppression. This protein inhibits T cell proliferation and transcription of cytokines and cyclins. The protein interacts with both mothers against decapentaplegic Drosophila homolog 2 and 4 to enhance their DNA binding activity. This interaction inhibits interleukin 2 transcription in T cells. [provided by RefSeq

Specifications

Antigen TOB1
Applications Immunohistochemistry (PFA fixed), Western Blot
Classification Polyclonal
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic phosphopeptide of human TOB1.
Dilution Immunohistochemistry (1:50-1:100) Western Blot (1:500-1000) The optimal working dilution should be determined by the end user.
Formulation In PBS, pH 7.4 (without Mg2+ and Ca2+), (50% glycerol, 0.02% sodium azide)
Gene TOB1
Gene Alias APRO6/MGC104792/MGC34446/PIG49/TOB/TROB/TROB1
Gene Symbols TOB1
Host Species Rabbit
Immunogen Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding S164 of human TOB1.
Purification Method Affinity purification
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10140
Test Specificity This antibody detects endogenous levels of TOB1 only when phosphorylated at serine 164.
Target Species Human, Mouse, Rat
Content And Storage Store at -20°C.
Avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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