TOP3B, Rabbit, Polyclonal Antibody, Abnova™

Catalog No.	Quantity
89-128-805	100 μL

Catalog No. 89-128-805 Supplier Abnova Corporation Supplier No. PAB27152

Description

Rabbit polyclonal antibody raised against synthetic peptide of TOP3B.

This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus relaxing the supercoils and altering the topology of DNA. The enzyme interacts with DNA helicase SGS1 and plays a role in DNA recombination, cellular aging and maintenance of genome stability. Alternative splicing of the C-terminus of this gene results in three transcript variants which have distinct tissue specificity; however, not all variants have been fully described. [provided by RefSeq

Specifications

• Antigen: TOP3B
• Applications: Immunohistochemistry, Western Blot
• Classification: Polyclonal
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Description: Rabbit polyclonal antibody raised against synthetic peptide of TOP3B.
• Dilution: Western Blot (1:500-1:1000) Immunohistochemistry (1:50-1:200) The optimal working dilution should be determined by the end user.
• Formulation: In PBS, pH 7.2 (0.05% sodium azide)
• Gene: TOP3B
• Gene Alias: FLJ39376
• Gene Symbols: TOP3B
• Host Species: Rabbit
• Immunogen: A synthetic peptide corresponding to human TOP3B.
• Purification Method: Antigen affinity purification
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 8940
• Test Specificity: TOP3B polyclonal antibody detects endogenous levels of TOP3B protein.
• Target Species: Human, Mouse
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid

For Research Use Only