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TP53I3 Rabbit anti-Human, Polyclonal Antibody, Abnova™

Catalog No. 89126563 Shop All Abnova Corporation Products
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89-126-563 100 μL
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Catalog No. 89-126-563 Supplier Abnova Corporation Supplier No. PAB24891
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Rabbit polyclonal antibody raised against synthetic peptide of TP53I3.

The protein encoded by this gene is similar to oxidoreductases, which are enzymes involved in cellular responses to oxidative stresses and irradiation. This gene is induced by the tumor suppressor p53 and is thought to be involved in p53-mediated cell death. It contains a p53 consensus binding site in its promoter region and a downstream pentanucleotide microsatellite sequence. P53 has been shown to transcriptionally activate this gene by interacting with the downstream pentanucleotide microsatellite sequence. The microsatellite is polymorphic, with a varying number of pentanucleotide repeats directly correlated with the extent of transcriptional activation by p53. It has been suggested that the microsatellite polymorphism may be associated with differential susceptibility to cancer. At least two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq

Specifications

Antigen TP53I3
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic peptide of TP53I3.
Dilution Western Blot (1:500-1:1000) The optimal working dilution should be determined by the end user.
Formulation In PBS, pH 7.2 (0.05% sodium azide)
Gene TP53I3
Gene Alias PIG3
Gene Symbols TP53I3
Host Species Rabbit
Immunogen A synthetic peptide corresponding to TP53I3.
Purification Method Antigen affinity purification
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 9540
Test Specificity TP53I3 polyclonal antibody detects endogenous levels of TP53I3 protein.
Target Species Human
Content And Storage Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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