MilliporeSigma™ Rabbit anti-TRAF3, Polyclonal,

Catalog No.	Quantity
ABE860MI	100 μg

Catalog No. ABE860MI Supplier MilliporeSigma™ Supplier No. ABE860

Description

Rabbit Polyclonal Antibody

Specifically detects TRAF3 in Human samples, and it is validated for Immunocytochemistry, Western Blotting

TNF receptor-associated factor 3 (TRAF3) has many alternative names including CAP-1, CD40 receptor-associated factor 1(CRAF1), CD40-binding protein(CD40BP) and LMP1-associated protein 1 (LAP1). TRAF3 regulates pathways leading to the activation of NF-kappa-B and MAP kinases, and plays a central role in the regulation of innate immune response. It modulates signaling pathways leading to the production of cytokines and interferon. As an essential constituent of several E3 ubiquitin-protein ligase complexes, TRAF3 promote 'Lys-63'-linked ubiquitination of target proteins. Moreover, TRAF3 undergoes both 'Lys-48'-linked and 'Lys-63'-linked ubiquitination in response to various stimuli and is deubiquitinated by OTUB1, OTUB2 and OTUD5.

Specifications

• Antigen: TRAF3
• Applications: Immunocytochemistry, Western Blot
• Classification: Polyclonal
• Formulation: Purified rabbit polyclonal in buffer containing PBS (pH 7.2) with 0.02% sodium azide.
• Gene Accession No.: Q13114
• Gene Symbols: TRAF3; CAP1; CRAF1
• Host Species: Rabbit
• Immunogen: TRAF3 antibody was raised against a 16 amino acid synthetic peptide from near the carboxy terminus of human TRAF3.
• Purification Method: Affinity Purified
• Quantity: 100 μg
• Regulatory Status: RUO
• Research Discipline: Epigenetics and Nuclear Function
• Primary or Secondary: Primary
• Target Species: Human
• Content And Storage: Stable for one year at 2°C to 8°C from date of receipt.

For Research Use Only