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TRAF6 Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™

Catalog No. 89116170 Shop All Abnova Corporation Products
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100 μg
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89-116-170 100 μg
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Catalog No. 89-116-170 Supplier Abnova Corporation Supplier No. PAB12896
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Description

Rabbit polyclonal antibody raised against synthetic peptide of TRAF6.

The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins are associated with, and mediate signal transduction from members of the TNF receptor superfamily. This protein mediates the signaling not only from the members of the TNF receptor superfamily, but also from the members of the Toll/IL-1 family. Signals from receptors such as CD40, TNFSF11/RANCE and IL-1 have been shown to be mediated by this protein. This protein also interacts with various protein kinases including IRAK1/IRAK, SRC and PKCzeta, which provides a link between distinct signaling pathways. This protein functions as a signal transducer in the NF-kappaB pathway that activates IkappaB kinase (IKK) in response to proinflammatory cytokines. The interaction of this protein with UBE2N/UBC13, and UBE2V1/UEV1A, which are ubiquitin conjugating enzymes catalyzing the formation of polyubiquitin chains, has been found to be required for IKK activation by this protein. Two alternatively spliced transcript variants encoding identical proteins have been reported. [provided by RefSeq

Specifications

Antigen TRAF6
Applications Immunocytochemistry, Western Blot
Classification Polyclonal
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic peptide of TRAF6.
Dilution Western Blot (1-2 ug/mL) The optimal working dilution should be determined by the end user.
Formulation In PBS (0.02% sodium azide)
Gene TRAF6
Gene Alias MGC:3310/RNF85
Gene Symbols TRAF6
Host Species Rabbit
Immunogen A synthetic peptide corresponding to C-terminus 14 amino acids of human TRAF6.
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 7189
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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