TYK2 Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™

Catalog No.	Quantity
89-128-870	100 μg

Catalog No. 89-128-870 Supplier Abnova Corporation Supplier No. PAB27216

Description

Rabbit polyclonal antibody raised against synthetic peptide of TYK2.

This gene encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E. [provided by RefSeq

Specifications

• Antigen: TYK2
• Applications: ELISA, Western Blot
• Classification: Polyclonal
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Description: Rabbit polyclonal antibody raised against synthetic peptide of TYK2.
• Dilution: Western Blot (1-2 ug/mL) The optimal working dilution should be determined by the end user.
• Formulation: In PBS (0.02% sodium azide)
• Gene: TYK2
• Gene Alias: JTK1
• Gene Symbols: TYK2
• Host Species: Rabbit
• Immunogen: A synthetic peptide corresponding to 17 amino acids at N-terminus of human TYK2.
• Purification Method: Peptide affinity purification
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 7297
• Test Specificity: At least three isoforms of TYK2 are known to exist; this antibody only detects the two longest isoforms.
• Target Species: Human, Mouse, Rat
• Content And Storage: Store at 4°C for three months. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid
• Isotype: IgG

For Research Use Only