TYK2 (phospho Y1054), Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™

Catalog No.	Quantity
89-133-438	100 μL

Catalog No. 89-133-438 Supplier Abnova Corporation Supplier No. PAB7734

Description

Rabbit polyclonal antibody raised against synthetic phosphopeptide of TYK2.

This gene encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E. [provided by RefSeq

Specifications

• Antigen: TYK2
• Applications: Western Blot
• Classification: Polyclonal
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Description: Rabbit polyclonal antibody raised against synthetic phosphopeptide of TYK2.
• Dilution: Western Blot (1:500-1:1000) The optimal working dilution should be determined by the end user.
• Formulation: In PBS (without Mg²⁺ and Ca²⁺), 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
• Gene: TYK2
• Gene Alias: JTK1
• Gene Symbols: TYK2
• Host Species: Rabbit
• Immunogen: Synthetic phosphopeptide corresponding to residues surrounding Y1054 of human TYK2.
• Purification Method: Immunoaffinity purification
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 7297
• Target Species: Human, Mouse, Rat
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid

For Research Use Only