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TYMS Rabbit anti-Bacteria, Human, Monkey, Mouse, Rat, Polyclonal Antibody, Abnova™

Catalog No. 89114982 Shop All Abnova Corporation Products
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89-114-982 100 μL
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Catalog No. 89-114-982 Supplier Abnova Corporation Supplier No. PAB11275

Description

Rabbit polyclonal antibody raised against recombinant TYMS.

Thymidylate synthase catalyzes the methylation of deoxyuridylate to deoxythymidylate using 5,10-methylenetetrahydrofolate (methylene-THF) as a cofactor. This function maintains the dTMP (thymidine-5-prime monophosphate) pool critical for DNA replication and repair. The enzyme has been of interest as a target for cancer chemotherapeutic agents. It is considered to be the primary site of action for 5-fluorouracil, 5-fluoro-2-prime-deoxyuridine, and some folate analogs. Expression of this gene and that of a naturally occuring antisense transcript rTSalpha (GeneID:55556) vary inversely when cell-growth progresses from late-log to plateau phase. [provided by RefSeq

Specifications

Antigen TYMS
Applications ELISA, Immunohistochemistry, Western Blot
Classification Polyclonal
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against recombinant TYMS.
Dilution Western Blot (1:1000) ELISA (1:100000) Immunohistochemistry (1:100) Immunoprecipitation (1:500) The optimal working dilution should be determined by the end user.
Formulation In antiserum (0.01% sodium azide)
Gene TYMS
Gene Alias HsT422/MGC88736/TMS/TS/TSase
Gene Symbols TYMS
Host Species Rabbit
Immunogen Recombinant protein corresponding to human TYMS.
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 7298
Target Species Bacteria, Human, Monkey, Mouse, Rat
Content And Storage Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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