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Description
The enzyme encoded by this gene catalyzes the first 2 steps, and at least 1 subsequent step, in the conversion of tyrosine to melanin. The enzyme has both tyrosine hydroxylase and dopa oxidase catalytic activities, and requires copper for function. Mutations in this gene result in oculocutaneous albinism, and nonpathologic polymorphisms result in skin pigmentation variation. The human genome contains a pseudogene similar to the 3' half of this gene. [provided by RefSeq]
Specifications
Specifications
| Antigen | TYR |
| Applications | Western Blot |
| Classification | Polyclonal |
| Concentration | 1 mg/mL |
| Conjugate | Unconjugated |
| Description | Rabbit polyclonal antibody raised against synthetic peptide of TYR. |
| Dilution | Western Blot (1:500-1:1000) The optimal working dilution should be determined by the end user. |
| Formulation | In 1X PBS, pH 7.2 (0.05% sodium azide) |
| Gene | TYR |
| Gene Alias | OCA1A/OCAIA/SHEP3 |
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