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UBB Rabbit anti-Human, Polyclonal Antibody, Abnova™

Catalog No. 89115449 Shop All Abnova Corporation Products
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100 μL
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89-115-449 100 μL
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Catalog No. 89-115-449 Supplier Abnova Corporation Supplier No. PAB11909

Description

Rabbit polyclonal antibody raised against full-length length recombinant UBB.

This gene encodes ubiquitin, one of the most conserved proteins known. Ubiquitin is required for ATP-dependent, nonlysosomal intracellular protein degradation of abnormal proteins and normal proteins with a rapid turnover. Ubiquitin is covalently bound to proteins to be degraded, and presumably labels these proteins for degradation. Ubiquitin also binds to histone H2A in actively transcribed regions but does not cause histone H2A degradation, suggesting that ubiquitin is also involved in regulation of gene expression. This gene consists of three direct repeats of the ubiquitin coding sequence with no spacer sequence. Consequently, the protein is expressed as a polyubiquitin precursor with a final amino acid after the last repeat. Aberrant form of this protein has been noticed in patients with Alzheimer's and Down syndrome. [provided by RefSeq]

Specifications

Antigen UBB
Applications Immunohistochemistry (PFA fixed)
Classification Polyclonal
Concentration Lot specific
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against full length length recombinant UBB.
Dilution Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (Formalin/PFA-fixed paraffin-embedded sections) (1:100) The optimal working dilution should be determined by the end user.
Formulation In 10mM PBS, pH 7.4 (1% BSA, 0.09% sodium azide)
Gene UBB
Gene Alias FLJ25987/MGC8385
Gene Symbols UBB
Host Species Rabbit
Immunogen Recombinant protein corresponding to full length human UBB.
Purification Method Immunoaffinity purification
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 7314
Target Species Human
Content And Storage Store at 4°C.
Form Liquid
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For Research Use Only

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