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UPF1, Rabbit, Polyclonal Antibody, Abnova™

Catalog No. 89131128 Shop All Abnova Corporation Products
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400 μL
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89-131-128 400 μL
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Catalog No. 89-131-128 Supplier Abnova Corporation Supplier No. PAB3694
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Description

Rabbit polyclonal antibody raised against synthetic peptide of UPF1.

This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located only in the cytoplasm. When translation ends, it interacts with the protein that is a functional homolog of yeast Upf2p to trigger mRNA decapping. Use of multiple polyadenylation sites has been noted for this gene. [provided by RefSeq

Specifications

Antigen UPF1
Applications ELISA, Western Blot
Classification Polyclonal
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic peptide of UPF1.
Dilution Western Blot (1:1000) The optimal working dilution should be determined by the end user.
Formulation In PBS (0.09% sodium azide)
Gene UPF1
Gene Alias FLJ43809/FLJ46894/HUPF1/KIAA0221/NORF1/RENT1/pNORF1
Gene Symbols UPF1
Host Species Rabbit
Immunogen A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human UPF1.
Purification Method Ammonium sulfate precipitation
Quantity 400 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5976
Target Species Human
Content And Storage Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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