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Description
Uroplakins (UPK) are integral membrane proteins that form 2-dimensional crystalline arrays termed urothelial plaques that cover more than 90% of the apical urothelial surface. The asymmetric unit membrane (AUM) forms the apical plaques of urothelium and is believed to strengthen the urothelial apical surface and prevent the cells from rupturing during bladder distention. The 4 major conserved integral membrane proteins of the AUM are UPK1A (MIM 611557), UPK1B (MIM 602380), UPK2 (MIM 611558), and UPK3A.[supplied by OMIM
Specifications
Specifications
| Antigen | UPK3A |
| Applications | Immunohistochemistry (PFA fixed) |
| Classification | Polyclonal |
| Concentration | Lot specific |
| Conjugate | Unconjugated |
| Description | Rabbit polyclonal antibody raised against synthetic peptide of UPK3A. |
| Dilution | Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:100) The optimal working dilution should be determined by the end user. |
| Formulation | In 10mM PBS, pH 7.4 (1% BSA, 0.09% sodium azide) |
| Gene | UPK3A |
| Gene Alias | MGC119178/UPIII/UPIIIA/UPK3 |
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