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VAV1 (phospho Y174), Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™
Rabbit polyclonal antibody raised against synthetic phosphopeptide of VAV1.
Supplier: Abnova Corporation PAB25422
Description
The protein encoded by this proto-oncogene is a member of the Dbl family of guanine nucleotide exchange factors (GEF) for the Rho family of GTP binding proteins. The protein is important in hematopoiesis, playing a role in T-cell and B-cell development and activation. This particular GEF has been identified as the specific binding partner of Nef proteins from HIV-1. Coexpression and binding of these partners initiates profound morphological changes, cytoskeletal rearrangements and the JNK/SAPK signaling cascade, leading to increased levels of viral transcription and replication. [provided by RefSeq
Sequence: E-I-Yp-E-DSpecifications
VAV1 | |
Polyclonal | |
Rabbit polyclonal antibody raised against synthetic phosphopeptide of VAV1. | |
In PBS (without Mg2+ and Ca2+), 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide) | |
VAV | |
Rabbit | |
Affinity purification | |
RUO | |
7409 | |
Store at -20°C. Aliquot to avoid repeated freezing and thawing. |
Western Blot | |
Unconjugated | |
Western Blot (1:500-1:1000) The optimal working dilution should be determined by the end user. | |
VAV1 | |
VAV1 | |
Synthetic phosphopeptide corresponding to residues surrounding Y174 of human VAV1. | |
100 μg | |
Primary | |
Human, Mouse, Rat | |
Liquid |
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