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VDR Rabbit anti-Human, Polyclonal Antibody, Abnova™

Catalog No. 89126536 Shop All Abnova Corporation Products
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89-126-536 100 μL
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Catalog No. 89-126-536 Supplier Abnova Corporation Supplier No. PAB24864
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Description

Rabbit polyclonal antibody raised against synthetic peptide of VDR.

This gene encodes the nuclear hormone receptor for vitamin D3. This receptor also functions as a receptor for the secondary bile acid lithocholic acid. The receptor belongs to the family of trans-acting transcriptional regulatory factors and shows sequence similarity to the steroid and thyroid hormone receptors. Downstream targets of this nuclear hormone receptor are principally involved in mineral metabolism though the receptor regulates a variety of other metabolic pathways, such as those involved in the immune response and cancer. Mutations in this gene are associated with type II vitamin D-resistant rickets. A single nucleotide polymorphism in the initiation codon results in an alternate translation start site three codons downstream. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq

Specifications

Antigen VDR
Applications Immunofluorescence, Immunohistochemistry (PFA fixed), Western Blot
Classification Polyclonal
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic peptide of VDR.
Dilution Western Blot (1:500-1:1000) Immunohistochemistry (1:50-1:200) Immunofluorescence (1:50-1:200) The optimal working dilution should be determined by the end user.
Formulation In 1X PBS, pH 7.2 (0.09% sodium azide)
Gene VDR
Gene Alias NR1I1
Gene Symbols VDR
Host Species Rabbit
Immunogen A synthetic peptide corresponding to VDR.
Purification Method Antigen affinity purification
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 7421
Test Specificity VDR polyclonal antibody detects endogenous levels of VDR protein.
Target Species Human
Content And Storage Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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