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VEGFA, Rabbit, Clone: SP28, Abnova™

Catalog No. 89112234 Shop All Abnova Corporation Products
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89-112-234 7 mL
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Catalog No. 89-112-234 Supplier Abnova Corporation Supplier No. MAB5374

Description

Rabbit monoclonal antibody raised against synthetic peptide of VEGFA.

This gene is a member of the PDGF/VEGF growth factor family and encodes a protein that is often found as a disulfide linked homodimer. This protein is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular permeability, inducing angiogenesis, vasculogenesis and endothelial cell growth, promoting cell migration, and inhibiting apoptosis. Elevated levels of this protein is linked to POEMS syndrome, also known as Crow-Fukase syndrome. Mutations in this gene have been associated with proliferative and nonproliferative diabetic retinopathy. Alternatively spliced transcript variants, encoding either freely secreted or cell-associated isoforms, have been characterized. There is also evidence for the use of non-AUG (CUG) translation initiation sites upstream of, and in-frame with the first AUG, leading to additional isoforms. [provided by RefSeq

Specifications

Antigen VEGFA
Applications Immunohistochemistry (Paraffin)
Classification Monoclonal
Clone SP28
Conjugate Unconjugated
Description Rabbit monoclonal antibody raised against synthetic peptide of VEGFA.
Dilution Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (Ready-to-use) The optimal working dilution should be determined by the end user.
Formulation Tissue culture supernatant in TBS buffer, pH 7.5 (1% BSA, 0.09% sodium azide).
Gene VEGFA
Gene Alias MGC70609/VEGF/VEGF-A/VPF
Gene Symbols VEGFA
Host Species Rabbit
Immunogen A synthetic peptide corresponding to N-terminus of human VEGFA
Quantity 7 mL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 7422
Test Specificity Molecular weight: 19-28KDa (reduced)
Target Species Human
Content And Storage Store at 4°C. Do not freeze.
Form Liquid
Isotype IgG
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