VEGFA Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic peptide of VEGFA.

Supplier:  Abnova Corporation PAB13525

Catalog No. 89-116-722

Description

This gene is a member of the PDGF/VEGF growth factor family and encodes a protein that is often found as a disulfide linked homodimer. This protein is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular permeability, inducing angiogenesis, vasculogenesis and endothelial cell growth, promoting cell migration, and inhibiting apoptosis. Elevated levels of this protein is linked to POEMS syndrome, also known as Crow-Fukase syndrome. Mutations in this gene have been associated with proliferative and nonproliferative diabetic retinopathy. Alternatively spliced transcript variants, encoding either freely secreted or cell-associated isoforms, have been characterized. There is also evidence for the use of non-AUG (CUG) translation initiation sites upstream of, and in-frame with the first AUG, leading to additional isoforms. [provided by RefSeq

Specifications

• Antigen: VEGFA
• Classification: Polyclonal
• Description: Rabbit polyclonal antibody raised against synthetic peptide of VEGFA.
• Formulation: Lyophilized from PBS, pH 7.4
• Gene Alias: MGC70609/VEGF/VEGF-A/VPF
• Host Species: Rabbit
• Quantity: 100 μg
• Primary or Secondary: Primary
• Test Specificity: This antibody reacts with VEGFA isoforms.
• Content And Storage: Store at 4°C on dry atmosphere. After reconstitution with deionized water store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

• Applications: ELISA, Western Blot
• Conjugate: Unconjugated
• Dilution: Western Blot (1-10 ug/mL) The optimal working dilution should be determined by the end user.
• Gene: VEGFA
• Gene Symbols: VEGFA
• Immunogen: A synthetic peptide corresponding to 20 amino acids of N-terminus of human VEGFA.
• Regulatory Status: RUO
• Gene ID (Entrez): 7422
• Target Species: Human, Mouse, Rat
• Form: Lyophilized

For Research Use Only