VRK1, Rabbit, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic peptide of VRK1.

Supplier:  Abnova Corporation PAB2882

Catalog No. 89-130-342

Description

This gene encodes a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases. This gene is widely expressed in human tissues and has increased expression in actively dividing cells, such as those in testis, thymus, fetal liver, and carcinomas. Its protein localizes to the nucleus and has been shown to promote the stability and nuclear accumulation of a transcriptionally active p53 molecule and, in vitro, to phosphorylate Thr18 of p53 and reduce p53 ubiquitination. This gene, therefore, may regulate cell proliferation. This protein also phosphorylates histone, casein, and the transcription factors ATF2 (activating transcription factor 2) and c-JUN. [provided by RefSeq

Specifications

• Antigen: VRK1
• Classification: Polyclonal
• Description: Rabbit polyclonal antibody raised against synthetic peptide of VRK1.
• Formulation: In PBS (0.09% sodium azide)
• Gene Alias: MGC117401/MGC138280/MGC142070
• Host Species: Rabbit
• Purification Method: Protein G purification
• Regulatory Status: RUO
• Gene ID (Entrez): 7443
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.

• Applications: ELISA, Western Blot
• Conjugate: Unconjugated
• Dilution: Western Blot (1:1000) The optimal working dilution should be determined by the end user.
• Gene: VRK1
• Gene Symbols: VRK1
• Immunogen: A synthetic peptide (conjugated with KLH) corresponding to internal region of human VRK1.
• Quantity: 400 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Form: Liquid

For Research Use Only