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WASL Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™

Catalog No. 89133468 Shop All Abnova Corporation Products
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89-133-468 100 μL
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Catalog No. 89-133-468 Supplier Abnova Corporation Supplier No. PAB7887
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Description

Rabbit polyclonal antibody raised against synthetic peptide of WASL.

The Wiskott-Aldrich syndrome (WAS) family of proteins share similar domain structure, and are involved in transduction of signals from receptors on the cell surface to the actin cytoskeleton. The presence of a number of different motifs suggests that they are regulated by a number of different stimuli, and interact with multiple proteins. Recent studies have demonstrated that these proteins, directly or indirectly, associate with the small GTPase, Cdc42, known to regulate formation of actin filaments, and the cytoskeletal organizing complex, Arp2/3. The WASL gene product is a homolog of WAS protein, however, unlike the latter, it is ubiquitously expressed and shows highest expression in neural tissues. It has been shown to bind Cdc42 directly, and induce formation of long actin microspikes. [provided by RefSeq

Specifications

Antigen WASL
Applications ELISA, Western Blot
Classification Polyclonal
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic peptide of WASL.
Dilution ELISA (1:2000) Western Blot (1:500) The optimal working dilution should be determined by the end user.
Formulation In PBS (50% glycerol, 1mg/mL BSA, 0.05% sodium azide)
Gene WASL
Gene Alias DKFZp779G0847/MGC48327/N-WASP/NWASP
Gene Symbols WASL
Host Species Rabbit
Immunogen A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human WASL.
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 8976
Test Specificity This N-WASP peptide sequence is 100% homologous to rat and mouse N-WASP, and has low homology to the corresponding region in the human WASP.
Target Species Human, Mouse, Rat
Content And Storage Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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