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WNT4 Rabbit anti-Bovine, Dog, Hamster, Horse, Human, Monkey, Mouse, Pig, Rat, Polyclonal Antibody, Abnova™

Catalog No. 89129879 Shop All Abnova Corporation Products
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89-129-879 50 μg
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Catalog No. 89-129-879 Supplier Abnova Corporation Supplier No. PAB28375
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Description

Rabbit polyconal antibody raised against synthetic peptide of WNT4.

The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family, and is the first signaling molecule shown to influence the sex-determination cascade. It encodes a protein which shows 98% amino acid identity to the Wnt4 protein of mouse and rat. This gene and a nuclear receptor known to antagonize the testis-determining factor play a concerted role in both the control of female development and the prevention of testes formation. This gene and another two family members, WNT2 and WNT7B, may be associated with abnormal proliferation in breast tissue. Mutations in this gene can result in Rokitansky-Kuster-Hauser syndrome and in SERKAL syndrome. [provided by RefSeq

Specifications

Antigen WNT4
Applications Immunohistochemistry (PFA fixed)
Classification Polyclonal
Conjugate Unconjugated
Description Rabbit polyconal antibody raised against synthetic peptide of WNT4.
Dilution Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (10 ug/ml) The optimal working dilution should be determined by the end user.
Formulation In PBS (0.09% sodium azide)
Gene WNT4
Gene Alias SERKAL/WNT-4
Gene Symbols WNT4
Host Species Rabbit
Immunogen A synthetic peptide corresponding to 14 amino acids at internal region of human WNT4.
Purification Method Immunoaffinity chromatography
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 54361
Test Specificity BLAST analysis of the peptide immunogen showed no homology with other human proteins, except WNT5A (71%).
Target Species Bovine, Canine, Equine, Hamster, Human, Monkey, Mouse, Pig, Rat
Content And Storage Store at 4°C. For long term storage store at -80°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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