WNT4 Rabbit anti-Bovine, Dog, Hamster, Horse, Human, Monkey, Mouse, Pig, Rat, Polyclonal Antibody, Abnova™
Rabbit polyconal antibody raised against synthetic peptide of WNT4.
Supplier: Abnova Corporation PAB28375
The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family, and is the first signaling molecule shown to influence the sex-determination cascade. It encodes a protein which shows 98% amino acid identity to the Wnt4 protein of mouse and rat. This gene and a nuclear receptor known to antagonize the testis-determining factor play a concerted role in both the control of female development and the prevention of testes formation. This gene and another two family members, WNT2 and WNT7B, may be associated with abnormal proliferation in breast tissue. Mutations in this gene can result in Rokitansky-Kuster-Hauser syndrome and in SERKAL syndrome. [provided by RefSeq
|Rabbit polyconal antibody raised against synthetic peptide of WNT4.|
|In PBS (0.09% sodium azide)|
|Bovine, Canine, Equine, Hamster, Human, Monkey, Mouse, Porcine, Rat|
|Immunohistochemistry (PFA fixed)|
|Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (10 ug/ml) The optimal working dilution should be determined by the end user.|
|A synthetic peptide corresponding to 14 amino acids at internal region of human WNT4.|
|BLAST analysis of the peptide immunogen showed no homology with other human proteins, except WNT5A (71%).|
|Store at 4°C. For long term storage store at -80°C.
Aliquot to avoid repeated freezing and thawing.
We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.
Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.Ok
For Research Use Only