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WWOX Rabbit anti-Human, Mouse, Polyclonal Antibody, Abnova™

Catalog No. 89128551 Shop All Abnova Corporation Products
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89-128-551 100 μL
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Catalog No. 89-128-551 Supplier Abnova Corporation Supplier No. PAB26906
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Rabbit polyclonal antibody raised against synthetic peptide of WWOX.

WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. This gene encodes a protein which contains 2 WW domains and a short-chain dehydrogenase/reductase domain (SRD). The highest normal expression of this gene is detected in hormonally regulated tissues such as testis, ovary, and prostate. This expression pattern and the presence of an SRD domain suggest a role for this gene in steroid metabolism. The encoded protein is more than 90% identical to the mouse protein, which is an essential mediator of tumor necrosis factor-alpha-induced apoptosis, suggesting a similar, important role in apoptosis for the human protein. In addition, there is evidence that this gene behaves as a suppressor of tumor growth. Alternative splicing of this gene generates transcript variants that encode different isoforms. [provided by RefSeq

Specifications

Antigen WWOX
Applications Immunofluorescence, Immunohistochemistry, Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic peptide of WWOX.
Dilution Western Blot (1:500-1:1000) Immunohistochemistry (1:50-1:200) Immunofluorescence (1:50-1:200) The optimal working dilution should be determined by the end user.
Formulation In PBS, pH 7.2 (0.05% sodium azide)
Gene WWOX
Gene Alias D16S432E/FOR/FRA16D/HHCMA56/PRO0128/SDR41C1/WOX1
Gene Symbols WWOX
Host Species Rabbit
Immunogen A synthetic peptide corresponding to human WWOX.
Purification Method Affinity purification
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 51741
Test Specificity WWOX polyclonal antibody detects endogenous levels of WWOX protein.
Target Species Human, Mouse
Content And Storage Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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