XAF1 Rabbit anti-Human, Polyclonal Antibody, Abnova™

Catalog No.	Quantity
89-116-378	100 μg

Catalog No. 89-116-378 Supplier Abnova Corporation Supplier No. PAB13125

Description

Rabbit polyclonal antibody raised against synthetic peptide of XAF1.

X-linked inhibitor of apoptosis (XIAP; MIM 300079) is a potent member of the IAP family. All members of this family possess baculoviral IAP (BIR) repeats, cysteine-rich domains of approximately 80 amino acids that bind and inhibit caspases (e.g., CASP3; MIM 600636). XIAP has 3 BIR domains and a C-terminal RING zinc finger that possesses E3 ubiquitin ligase (see MIM 601623) activity. XAF1 antagonizes the anticaspase activity of XIAP and may be important in mediating apoptosis resistance in cancer cells (Liston et al., 2001 [PubMed 11175744]).[supplied by OMIM

Specifications

• Antigen: XAF1
• Applications: Western Blot
• Classification: Polyclonal
• Conjugate: Unconjugated
• Description: Rabbit polyclonal antibody raised against synthetic peptide of XAF1.
• Dilution: Western Blot (1-2 ug/mL) The optimal working dilution should be determined by the end user.
• Formulation: In PBS (0.02% sodium azide)
• Gene: XAF1
• Gene Alias: BIRC4BP/HSXIAPAF1/XIAPAF1
• Gene Symbols: XAF1
• Host Species: Rabbit
• Immunogen: A synthetic peptide corresponding to internal region 16 amino acids of human XAF1.
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 54739
• Test Specificity: Multiple isoforms of XAF-1 exist and a doublet at ∼30 KDa can be seen using anti-XAF-1 (IN).
• Target Species: Human
• Content And Storage: Store at 4°C for three months. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid

For Research Use Only