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Description
This gene encodes a member of the RecA/Rad51-related protein family that participates in homologous recombination to maintain chromosome stability and repair DNA damage. This gene functionally complements Chinese hamster irs1SF, a repair-deficient mutant that exhibits hypersensitivity to a number of different DNA-damaging agents and is chromosomally unstable. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq
Specifications
Specifications
| Antigen | XRCC3 |
| Applications | Immunohistochemistry (PFA fixed), Western Blot |
| Classification | Polyclonal |
| Concentration | 1 mg/mL |
| Conjugate | Unconjugated |
| Description | Rabbit polyclonal antibody raised against synthetic peptide of XRCC3. |
| Dilution | Western Blot (1:500-1000) Immunohistochemistry (1:50-1:200) The optimal working dilution should be determined by the end user. |
| Formulation | In 1X PBS, pH 7.2 (0.05% sodium azide) |
| Gene | XRCC3 |
| Gene Symbols | XRCC3 |
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