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XRCC5 Rabbit anti-Human, Polyclonal Antibody, Abnova™

Catalog No. 89121149 Shop All Abnova Corporation Products
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100 μL
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Catalog No. Quantity
89-121-149 100 μL
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Catalog No. 89-121-149 Supplier Abnova Corporation Supplier No. PAB19620

Description

Rabbit polyclonal antibody raised against synthetic peptide of XRCC5.

The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by nonhomologous end joining and the completion of V(D)J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. [provided by RefSeq

Specifications

Antigen XRCC5
Applications Immunohistochemistry (PFA fixed)
Classification Polyclonal
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic peptide of XRCC5.
Dilution Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:100) The optimal working dilution should be determined by the end user.
Formulation In PBS, pH 7.6 (1% BSA, 0.09% sodium azide)
Gene XRCC5
Gene Alias FLJ39089/KARP-1/KARP1/KU80/KUB2/Ku86/NFIV
Gene Symbols XRCC5
Host Species Rabbit
Immunogen A synthetic peptide corresponding to internal region of human XRCC5.
Purification Method Immunoaffinity purification
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 7520
Target Species Human
Content And Storage Store at 4°C. Do not freeze.
Form Liquid
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