ZYX, Rabbit, Polyclonal Antibody, Abnova™

Catalog No.	Quantity
89-121-348	100 μg

Catalog No. 89-121-348 Supplier Abnova Corporation Supplier No. PAB19818

Description

Rabbit polyclonal antibody raised against synthetic peptide of ZYX.

Focal adhesions are actin-rich structures that enable cells to adhere to the extracellular matrix and at which protein complexes involved in signal transduction assemble. Zyxin is a zinc-binding phosphoprotein that concentrates at focal adhesions and along the actin cytoskeleton. Zyxin has an N-terminal proline-rich domain and three LIM domains in its C-terminal half. The proline-rich domain may interact with SH3 domains of proteins involved in signal transduction pathways while the LIM domains are likely involved in protein-protein binding. Zyxin may function as a messenger in the signal transduction pathway that mediates adhesion-stimulated changes in gene expression and may modulate the cytoskeletal organization of actin bundles. Alternative splicing results in multiple transcript variants that encode the same isoform. [provided by RefSeq

Specifications

• Antigen: ZYX
• Applications: ELISA, Immunofluorescence, Western Blot
• Classification: Polyclonal
• Conjugate: Unconjugated
• Description: Rabbit polyclonal antibody raised against synthetic peptide of ZYX.
• Dilution: ELISA (1:32000) Western Blot (1:500-1000) Immunofluorescence (1:50-1:200) The optimal working dilution should be determined by the end user.
• Formulation: In serum (0.02% sodium azide)
• Gene: ZYX
• Gene Alias: ESP-2/HED-2
• Gene Symbols: ZYX
• Host Species: Rabbit
• Immunogen: A synthetic peptide corresponding to 15 amino acids near internal region of human ZYX.
• Purification Method: Protein A purification
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 7791
• Target Species: Human
• Content And Storage: Store at 4°C for three months. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid

For Research Use Only