Invitrogen™ RAC2 Polyclonal Antibody

Goat Polyclonal Antibody

Supplier:  Invitrogen™ PA19091

Catalog No. 01-674-673

Description

This antibody is predicted to react with mouse and rat based on sequence homology. This antibody is tested in Peptide ELISA: antibody detection limit dilution 32,000.

RAC, a small GTPase in the ras family, regulates the formation of membrane ruffles, lamellipodia and filopodia. It is involved in cytoskeletal actin organization and transformation. The p21 activated kinases (PAKs) are direct targets of active Rac and Cdc42 which can induce the assembly of polarized cytoskeletal structures when expressed in fibroblasts. RAC1 and RAC2 are also essential components of NADPH oxidase, the enzyme responsible for generating free radicals.

Specifications

• Antigen: RAC2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: RAC2
• Gene Alias: AI323801; AI452260; EN-7; EN-7 protein; Gx; HSPC022; p21-Rac2; Protein EN-7; RAC2; RAS-related C3 botulinum substrate 2; ras-related C3 botulinum toxin substrate 2; ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2); Ras-related C3 botulinum toxin substrate 3 (rho family, small GTP-binding protein Rac2); small G protein
• Host Species: Goat
• Purification Method: Ammonium sulfate precipitation
• Regulatory Status: RUO
• Gene ID (Entrez): 5880
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.5 mg/mL
• Formulation: TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P15153
• Gene Symbols: RAC2
• Immunogen: Synthetic peptide corresponding to the C terminus amino acids PQPTRQQKRACSLL (aa 179-192).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG