Invitrogen™ RACGAP1 Monoclonal Antibody (23A8)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA120580

Catalog No. MA120580

Description

Recommended positive controls: rat brain microsomal protein. MA1-20580 detects a band of approximately 21 kDa.

RAC, a small GTPase in the ras family, regulates the formation of membrane ruffles, lamellipodia and filopodia. It is involved in cytoskeletal actin organization and transformation. The p21 activated kinases (PAKs) are direct targets of active Rac and Cdc42 which can induce the assembly of polarized cytoskeletal structures when expressed in fibroblasts. RAC1 and RAC2 are also essential components of NADPH oxidase, the enzyme responsible for generating free radicals.

Specifications

• Antigen: RACGAP1
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: TBS with 30% glycerol and 0.05% sodium azide
• Gene Accession No.: Q9H0H5, Q9WVM1
• Gene Symbols: RACGAP1
• Immunogen: Recombinant protein containing the full length human Rac1.
• Quantity: 50 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG2b

• Applications: Immunohistochemistry (Frozen), Immunoprecipitation, Western Blot
• Clone: 23A8
• Conjugate: Unconjugated
• Gene: RACGAP1
• Gene Alias: AI227039; AI327394; AKT; Band25; CYK4; GAP; gtl11; GTPase; HsCYK-4; ID; ID-GAP; KIAA1478; Male germ cell RacGap; MGC99656; MgcRacGAP; mKIAA1478; PKB; PKB-ALPHA; PRKBA; protein CYK4 homolg; Protein CYK4 homolog; RAC; Rac GTPase activating protein 1; Rac GTPase-activating protein 1; RAC-ALPHA; Racgap1
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 26934, 29127, 315298
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov