Invitrogen™ RACGAP1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA529698

Catalog No. PIPA529698

Description

Recommended positive controls: 293T, A431, Jurkat, Raji. Predicted reactivity: Mouse (81%), Rat (82%), Rhesus Monkey (100%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

RAC, a small GTPase in the ras family, regulates the formation of membrane ruffles, lamellipodia and filopodia. It is involved in cytoskeletal actin organization and transformation. The p21 activated kinases (PAKs) are direct targets of active Rac and Cdc42 which can induce the assembly of polarized cytoskeletal structures when expressed in fibroblasts. RAC1 and RAC2 are also essential components of NADPH oxidase, the enzyme responsible for generating free radicals.

Specifications

• Antigen: RACGAP1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: RACGAP1
• Gene Alias: AI227039; AI327394; AKT; Band25; CYK4; GAP; gtl11; GTPase; HsCYK-4; ID; ID-GAP; KIAA1478; Male germ cell RacGap; MGC99656; MgcRacGAP; mKIAA1478; PKB; PKB-ALPHA; PRKBA; protein CYK4 homolg; Protein CYK4 homolog; RAC; Rac GTPase activating protein 1; Rac GTPase-activating protein 1; RAC-ALPHA; Racgap1
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 29127
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: Q9H0H5
• Gene Symbols: RACGAP1
• Immunogen: Recombinant fragment corresponding to a region within amino acids 395 and 632 of Human RACGAP1.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov