Invitrogen™ RAD1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA552326

Catalog No. PIPA552326

Description

Immunogen sequence: GLREAFSELD MTSEVLQITM SPDKPYFRLS TFGNAGSSHL DYPKDSDLME AFHCNQTQVN RYKISLLKPS TKALVLSCKV SIRTDNRGFL SLQYMIRNED GQICFVEYYC CPDEEVPESE S Highest antigen sequence identity to the following orthologs: Mouse - 91%, Rat - 91%.

Rad1 is a component of a heterotrimeric PCNA-like complex that contains Rad9 and Hus1 proteins. This complex is involved in the 9-1-1 cell cycle checkpoing response complex that plays a major role in DNA repair, by associating with Rad17 and several components of the PCNA-loading heteropentamer replication factor C. Mutants has been shown to partially restore radiation resistance and G2-checkpoint activity. It has also been shown to possess exonuclease activity.

Specifications

• Antigen: RAD1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: RAD1
• Gene Alias: cell cycle checkpoint protein Hrad1; cell cycle checkpoint protein RAD1; checkpoint control protein HRAD1; DNA repair exonuclease rad1 homolog; DNA repair exonuclease REC1; exonuclease homolog RAD1; hRAD1; mRAD1; RAD1; RAD1 checkpoint clamp component; RAD1 checkpoint DNA exonuclease; RAD1 homolog; RAD1 homolog (S. pombe); rad1-like DNA damage checkpoint protein; REC1
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 5810
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: O60671
• Gene Symbols: RAD1
• Immunogen: Recombinant protein corresponding to Human RAD1. Recombinant protein control fragment (Product #RP-89473).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG