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Invitrogen™ RAD17 Polyclonal Antibody
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Catalog No. PA14132
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100 μg
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Catalog No. Quantity
PA14132 100 μg
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Catalog No. PA14132 Supplier Invitrogen™ Supplier No. PA14132
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Description

Rabbit Polyclonal Antibody

PA1-4132 detects human RAD17. PA1-4132 has been successfully used in Western blot procedures. By Western blot this antibody detects a ~66 kDa protein representing RAD17 in human heart lysate. The PA1-4132 immunogen is a synthetic peptide corresponding to residues N(2) Q V T D W V D P S F D D F(15) of human RAD17.

Rad17 is essential for sustained cell growth, maintenance of chromosomal stability, and ATR-dependent checkpoint activation upon DNA damage. It has a weak ATPase activity required for binding to chromatin. Rad17 also participates in the recruitment of the RAD1-RAD9-HUS1 complex and RHNO1 onto chromatin, and in CHEK1 activation. May also serve as a sensor of DNA replication progression, and may be involved in homologous recombination.
TRUSTED_SUSTAINABILITY

Specifications

Antigen RAD17
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene Rad17
Gene Accession No. O75943
Gene Alias CCYC; cell cycle checkpoint protein (RAD17); cell cycle checkpoint protein RAD17; DNA damage checkpoint control protein RAD17; DNA repair exonuclease RAD17; FLJ41520; hRad17; MmRad24; R24L; RAD1 homolog; RAD17; RAD17 (Ser647); RAD17 checkpoint clamp loader component; RAD17 homolog; RAD17 homolog (S. pombe); Rad17 like protein; Rad17-like protein; Rad17p; RAD17SP; RAD24; RF-C activator 1 homolog; RF-C/activator 1 homolog; YOR368W
Gene Symbols Rad17
Host Species Rabbit
Immunogen Synthetic peptide corresponding to residues N(2) Q V T D W V D P S F D D F(15) of human RAD17.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5884
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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